A recent case report by Prof. Yong He and Dr. Baotao Huang from West China Hospital, Sichuan University, published in Catheterization and Cardiovascular Interventions, highlights how AI-powered CtaPlus software — integrating CCTA analysis and CCTA-angiography fusion — can support procedural planning for complex CTO PCI.

🔍 Key Highlights

• 3D coronary reconstruction to visualize CTO morphology, lesion course, and branch anatomy.

• AI-powered plaque characterization to identify calcified and relatively softer plaque regions.

• Vessel-specific myocardial perfusion assessment: the RCA supplied 77.8% of the right ventricle and 29.8% of the left ventricle.

• CCTA-angiography co-registration to distinguish the true proximal stump from a calcified pseudo-opening and support the antegrade crossing strategy.

📊 Post-PCI Physiology

RCA μFR: 0.93 | LAD μFR: 0.83

These findings contributed to the reassessment of the originally planned staged revascularization strategy.

💡 Takeaway

This case demonstrates how coronary anatomy, plaque morphology, image fusion, and physiology can be integrated into a more comprehensive workflow for complex PCI, providing operators with a more intuitive “panoramic view” for procedural planning and decision-making.

📖 Huang B, He Y. Catheterization and Cardiovascular Interventions. 2026;108(1):21–25.

DOI: 10.1002/ccd.70615

Note: QFR is a registered trademark of Pulse Medical in China. In international markets, Pulse Medical uses μFR for its angiography-derived physiological assessment technology. QFR terminology shown in this post follows the original scientific publication.

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